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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2321145
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fbxw7
Name: F-box and WD repeat domain containing 7
Acc ID: CHEBI:4610
Term: dimethylselenide
Definition: An organoselenium compound of two methyl groups covalently bound to a selenium.
Chemical ID: MESH:C013503
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbxw7multiple interactionsISOFBXW7 (Homo sapiens)6480464CTD[[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of FBXW7-AS1 mRNA] which results in increased expression of FBXW7 mRNA; [[Ozone results in increased oxidation of dimethylselenide] which results in increased expression of FBXW7-AS1 mRNA] which results in increased expression of FBXW7 mRNAPMID:33656867
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