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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736627
Species: Homo sapiens
RGD Object: Gene
Symbol: FN1
Name: fibronectin 1
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FN1decreases expressionEXP 6480464CTDtrichostatin A results in decreased expression of FN1 mRNAPMID:22228707
FN1increases expressionEXP 6480464CTDtrichostatin A results in increased expression of FN1 mRNAPMID:24935251 PMID:26272509
FN1multiple interactionsEXP 6480464CTD[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FN1 mRNA; trichostatin A inhibits the reaction [Glucose results in increased expression of FN1 mRNA]PMID:22228707 PMID:27188386
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