GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CDKN1A | affects expression | EXP | | 6480464 | CTD | [trichostatin A affects the expression of DNMT3B protein] which affects the expression of CDKN1A mRNA; trichostatin A affects the expression of CDKN1A protein | PMID:18544619 PMID:26559563 | CDKN1A | increases expression | EXP | | 6480464 | CTD | trichostatin A results in increased expression of CDKN1A mRNA; trichostatin A results in increased expression of CDKN1A protein | PMID:15179185 PMID:16009488 PMID:16051188 PMID:16865256 PMID:17230511 PMID:17431121 PMID:17653085 PMID:18223691 PMID:19234609 PMID:19606018 PMID:23770000 PMID:24935251 PMID:25699604 PMID:26559563 | CDKN1A | multiple interactions | EXP | | 6480464 | CTD | [decitabine co-treated with trichostatin A] affects the expression of CDKN1A mRNA; [decitabine co-treated with trichostatin A] results in increased expression of CDKN1A protein; [trichostatin A co-treated with Bortezomib] results in increased expression of CDKN1A mRNA; [trichostatin A co-treated with Bortezomib] results in increased expression of CDKN1A protein; Etoposide promotes the reaction [trichostatin A results in increased expression of CDKN1A protein]; Hydroxyurea inhibits the reaction [trichostatin A results in increased expression of CDKN1A protein]; MIR106B mRNA affects the reaction [trichostatin A affects the expression of CDKN1A protein]; MIR106B mRNA inhibits the reaction [trichostatin A results in increased expression of CDKN1A mRNA]; Tretinoin promotes the reaction [trichostatin A results in increased expression of CDKN1A mRNA]; Tretinoin promotes the reaction [trichostatin A results in increased expression of CDKN1A protein]; trichostatin A promotes the reaction [decitabine results in increased expression of CDKN1A mRNA]; trichostatin A promotes the reaction [decitabine results in increased expression of CDKN1A protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of CDKN1A protein] | PMID:16043219 PMID:17185465 PMID:17431121 PMID:17653085 PMID:18223691 PMID:21345073 PMID:25699604 PMID:26559563 | CDKN1A | multiple interactions | ISO | Cdkn1a (Rattus norvegicus) | 6480464 | CTD | trichostatin A inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein] | PMID:25015661 | | ||||||||||||||||||||||
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