GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dusp1 | increases expression | EXP | | 6480464 | CTD | trichostatin A results in increased expression of DUSP1 mRNA | PMID:11689710 | Dusp1 | increases activity | ISO | DUSP1 (Homo sapiens) | 6480464 | CTD | trichostatin A results in increased activity of DUSP1 protein | PMID:21911040 | Dusp1 | increases expression | ISO | DUSP1 (Homo sapiens) | 6480464 | CTD | trichostatin A results in increased expression of DUSP1 mRNA | PMID:24935251 PMID:26272509 | Dusp1 | multiple interactions | ISO | DUSP1 (Homo sapiens) | 6480464 | CTD | DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]]; DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]; DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JUN protein]]; DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]]; DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]]; DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]]; trichostatin A promotes the reaction [arsenite results in increased expression of DUSP1 mRNA] | PMID:11689710 PMID:21911040 | | ||||||||||||||||||||||
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