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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732227
Species: Homo sapiens
RGD Object: Gene
Symbol: NR3C1
Name: nuclear receptor subfamily 3 group C member 1
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR3C1affects expressionEXP 6480464CTDtrichostatin A affects the expression of NR3C1 mRNAPMID:28542535
NR3C1decreases expressionEXP 6480464CTDtrichostatin A results in decreased expression of NR3C1 mRNA alternative form; trichostatin A results in decreased expression of NR3C1 protein alternative formPMID:17498915
NR3C1increases expressionEXP 6480464CTDtrichostatin A results in increased expression of NR3C1 mRNA; trichostatin A results in increased expression of NR3C1 mRNA alternative form; trichostatin A results in increased expression of NR3C1 protein alternative formPMID:17498915 PMID:24935251
NR3C1multiple interactionsISONr3c1 (Rattus norvegicus)6480464CTDtrichostatin A inhibits the reaction [Dexamethasone affects the localization of NR3C1 protein]; trichostatin A inhibits the reaction [HSP90AA1 protein binds to NR3C1 protein]PMID:31778773
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