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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731028
Species: Homo sapiens
RGD Object: Gene
Symbol: SGK1
Name: serum/glucocorticoid regulated kinase 1
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SGK1increases expressionEXP 6480464CTDtrichostatin A results in increased expression of SGK1 mRNAPMID:24935251 PMID:26272509
SGK1multiple interactionsEXP 6480464CTD[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SGK1 mRNAPMID:27188386
SGK1multiple interactionsISOSgk1 (Mus musculus)6480464CTDtrichostatin A inhibits the reaction [Dexamethasone results in increased expression of SGK1 mRNA]PMID:23946490
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