Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70988
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akap12
Name: A-kinase anchoring protein 12
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akap12increases expressionEXP 6480464CTDtrichostatin A results in increased expression of AKAP12 mRNAPMID:12445420
Akap12decreases expressionISOAKAP12 (Homo sapiens)6480464CTDtrichostatin A results in decreased expression of AKAP12 mRNAPMID:24935251 PMID:26272509
Akap12increases expressionISOAKAP12 (Homo sapiens)6480464CTDtrichostatin A results in increased expression of AKAP12 mRNAPMID:26705709
Akap12multiple interactionsISOAKAP12 (Homo sapiens)6480464CTD[[Decitabine co-treated with trichostatin A] affects the methylation of AKAP12 promoter] which affects the expression of AKAP12 mRNA; [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AKAP12 mRNAPMID:18803327 PMID:27188386
Go Back to source page   Continue to Ontology report