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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621250
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gata3
Name: GATA binding protein 3
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gata3increases expressionISOGATA3 (Homo sapiens)6480464CTDtrichostatin A results in increased expression of GATA3 mRNAPMID:24935251 PMID:26272509
Gata3multiple interactionsISOGATA3 (Homo sapiens)6480464CTD[Decitabine co-treated with trichostatin A] results in decreased expression of GATA3 mRNA; [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNAPMID:17891453 PMID:27188386
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