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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620396
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kl
Name: Klotho
Acc ID: CHEBI:45869
Term: estriol 3-O-(beta-D-glucuronide)
Definition: A steroid glucosiduronic acid that is the 3-beta-D-glucuronide of estriol; a steroid hormone ligand recognised by the monoclonal antibody 4155.
Chemical ID: MESH:C022810
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klincreases hydrolysisISORGD:7327846480464CTDKL protein results in increased hydrolysis of estriol 3-glucuronide

PMID:14701853
Klmultiple interactionsISORGD:7327846480464CTDestriol 3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides]

PMID:14701853
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