GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkb1 | multiple interactions | EXP | | 6480464 | CTD | ITGAM protein affects the reaction [Paclitaxel affects the localization of and results in increased activity of [NFKB1 protein binds to RELA protein]]; Paclitaxel affects the localization of and results in increased activity of [NFKB1 protein binds to RELA protein] | PMID:11123339 | Nfkb1 | increases expression | ISO | Nfkb1 (Rattus norvegicus) | 6480464 | CTD | Paclitaxel results in increased expression of NFKB1 mRNA | PMID:35921949 PMID:36966900 | Nfkb1 | multiple interactions | ISO | Nfkb1 (Rattus norvegicus) | 6480464 | CTD | Hesperidin inhibits the reaction [Paclitaxel results in increased expression of NFKB1 mRNA] | PMID:35921949 PMID:36966900 | Nfkb1 | multiple interactions | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | [Paclitaxel co-treated with Metformin] results in decreased expression of NFKB1 mRNA; Curcumin inhibits the reaction [Paclitaxel results in increased activity of NFKB1 protein] | PMID:16243823 PMID:29309887 | |
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