GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NFKBIA | decreases phosphorylation | EXP | | 6480464 | CTD | vorinostat results in decreased phosphorylation of NFKBIA protein | PMID:17681667 PMID:19509267 | NFKBIA | multiple interactions | EXP | | 6480464 | CTD | TNFSF10 protein promotes the reaction [vorinostat results in decreased phosphorylation of NFKBIA protein]; vorinostat inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; vorinostat inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; vorinostat inhibits the reaction [TNF protein results in increased ubiquitination of NFKBIA protein]; vorinostat results in increased cleavage of and results in increased activity of NFKBIA protein | PMID:16377638 PMID:17681667 PMID:19509267 | | ||||||||||||||||||||||
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