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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:45504
Term: 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID
Definition: null
Chemical ID: MESH:D012460
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7374146480464CTD4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Sulfasalazine results in decreased activity of SLC7A11 protein] which results in increased expression of CDH1 mRNA], [Sulfasalazine results in decreased activity of SLC7A11 protein] which results in increased expression of CDH1 mRNA

PMID:19015640
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.