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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2557
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ephx1
Name: epoxide hydrolase 1
Acc ID: CHEBI:45422
Term: propionamide
Definition: A monocarboxylic acid amide obtained by the formal condensation of propionic acid with ammonia.
Chemical ID: MESH:C034666
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ephx1decreases activityEXP 6480464CTDpropionamide analog results in decreased activity of EPHX1 proteinPMID:18363382
Ephx1decreases activityISOEphx1 (Mus musculus)6480464CTDpropionamide analog results in decreased activity of EPHX1 proteinPMID:18363382
Ephx1multiple interactionsISOEphx1 (Mus musculus)6480464CTD[propionamide analog results in decreased activity of EPHX1 protein] which results in increased glutathionylation of naphthalenePMID:18363382
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