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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69295
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Asic5
Name: acid sensing ion channel subunit family member 5
Acc ID: CHEBI:45081
Term: pentamidine
Definition: A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Chemical ID: MESH:D010419
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Asic5decreases activityISORGD:7360196480464CTDPentamidine results in decreased activity of ASIC5 protein

PMID:21828194
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