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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731729
Species: Mus musculus
RGD Object: Gene
Symbol: Casp1
Name: caspase 1
Acc ID: CHEBI:4488
Term: diallyl disulfide
Definition: An organic disulfide where the organic group specified is allyl. It has been isolated from garlic and other species of the genus Allium.
Chemical ID: MESH:C028009
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp1multiple interactionsEXP 6480464CTDdiallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of CASP1 protein modified form]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of CASP1 protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased cleavage of CASP1 protein]PMID:34896185 PMID:35526736
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