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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp8
Name: caspase 8
Acc ID: CHEBI:4488
Term: diallyl disulfide
Definition: An organic disulfide where the organic group specified is allyl. It has been isolated from garlic and other species of the genus Allium.
Chemical ID: MESH:C028009
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp8increases cleavageISOCASP8 (Homo sapiens)6480464CTDdiallyl disulfide results in increased cleavage of CASP8 proteinPMID:30677442
Casp8multiple interactionsISOCASP8 (Homo sapiens)6480464CTDdiallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP8 protein]PMID:30677442
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