GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nqo1 | increases activity | EXP | | 6480464 | CTD | diallyl disulfide results in increased activity of NQO1 protein | PMID:8339252 | Nqo1 | multiple interactions | EXP | | 6480464 | CTD | diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]; diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 protein] | PMID:24293383 | Nqo1 | increases expression | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | diallyl disulfide results in increased expression of NQO1 mRNA; diallyl disulfide results in increased expression of NQO1 protein | PMID:34896185 | Nqo1 | multiple interactions | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | diallyl disulfide inhibits the reaction [Ethanol results in increased expression of NQO1 protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 mRNA]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 protein]; diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 mRNA]] | PMID:34896185 PMID:35526736 | |
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