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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621676
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acta2
Name: actin alpha 2, smooth muscle
Acc ID: CHEBI:4480
Term: diacetylmonoxime
Definition: A ketoxime obtained via formal condensation of butane-2,3-dione with hydroxylamine. It is a reversible myosin ATPase inhibitor.
Chemical ID: MESH:C004717
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acta2decreases expressionEXP 6480464CTDdiacetylmonoxime results in decreased expression of ACTA2PMID:11868461
Acta2affects localizationISOACTA2 (Homo sapiens)6480464CTDdiacetylmonoxime affects the localization of ACTA2 proteinPMID:11591817
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