GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Prkcd | affects response to substance | ISO | Prkcd (Mus musculus) | 6480464 | CTD | PRKCD protein affects the susceptibility to Dextromethorphan | PMID:34740715 | Prkcd | multiple interactions | ISO | Prkcd (Mus musculus) | 6480464 | CTD | [PRKCD protein affects the susceptibility to Dextromethorphan] which affects the activity of and affects the localization of NFE2L2 protein; Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]; Dextromethorphan results in increased expression of and results in increased phosphorylation of PRKCD protein; PRKCD protein affects the reaction [Dextromethorphan affects the expression of GCLC mRNA]; PRKCD protein affects the reaction [Dextromethorphan affects the expression of GCLM mRNA]; rostafuroxin inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; rostafuroxin inhibits the reaction [Dextromethorphan results in increased phosphorylation of PRKCD protein]; rottlerin inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; rottlerin inhibits the reaction [Dextromethorphan results in increased phosphorylation of PRKCD protein]; traxoprodil mesylate inhibits the reaction [Dextromethorphan promotes the reaction [PRKCD protein modified form binds to GRIN2B protein]]; traxoprodil mesylate inhibits the reaction [Dextromethorphan results in increased phosphorylation of PRKCD protein] | PMID:34740715 | | ||||||||||||||||||||||
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