Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731346
Species: Mus musculus
RGD Object: Gene
Symbol: Ido1
Name: indoleamine 2,3-dioxygenase 1
Acc ID: CHEBI:4469
Term: (S)-amphetamine
Definition: A 1-phenylpropan-2-amine that has S configuration.
Chemical ID: MESH:D003913
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ido1increases expressionEXP 6480464CTDDextroamphetamine results in increased expression of IDO1 proteinPMID:31760073
Ido1multiple interactionsEXP 6480464CTD[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in increased expression of IDO1 protein]; IDO1 protein affects the reaction [Dextroamphetamine results in decreased activity of SOD2 protein]; Valproic Acid inhibits the reaction [Dextroamphetamine results in increased expression of IDO1 protein]PMID:31760073
Go Back to source page   Continue to Ontology report