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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308198
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fosb
Name: FosB proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:4469
Term: (S)-amphetamine
Definition: A 1-phenylpropan-2-amine that has S configuration.
Chemical ID: MESH:D003913
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosbaffects expressionEXP 6480464CTDDextroamphetamine affects the expression of FOSB proteinPMID:12726824
Fosbincreases expressionEXP 6480464CTDDextroamphetamine results in increased expression of FOSB mRNA; Dextroamphetamine results in increased expression of FOSB proteinPMID:1347779 PMID:16678866
Fosbmultiple interactionsEXP 6480464CTD[Phencyclidine co-treated with Dextroamphetamine] results in increased expression of FOSB protein; Dextroamphetamine deficiency affects the reaction [Dextroamphetamine affects the expression of FOSB protein]PMID:12726824 PMID:16678866
Fosbincreases expressionISOFosb (Mus musculus)6480464CTDDextroamphetamine results in increased expression of FOSB mRNAPMID:12558987
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