GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HMOX1 | multiple interactions | EXP | | 6480464 | CTD | Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of HMOX1 protein]] | PMID:36858639 | HMOX1 | increases expression | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | Dexmedetomidine results in increased expression of HMOX1 mRNA | PMID:36027947 | HMOX1 | multiple interactions | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of HMOX1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 protein]]; atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of HMOX1 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of HMOX1 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 mRNA]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of HMOX1 protein]; Dexmedetomidine results in increased expression of and results in increased activity of HMOX1 protein | PMID:30597158 PMID:36027947 | |
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