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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589741
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rgs16
Name: regulator of G-protein signaling 16
Acc ID: CHEBI:44616
Term: afimoxifene
Definition: A tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen.
Chemical ID: MESH:C016601
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rgs16increases expressionISORGS16 (Homo sapiens)6480464CTDafimoxifene results in increased expression of RGS16 mRNAPMID:19153601
Rgs16multiple interactionsISORGS16 (Homo sapiens)6480464CTDGPER1 protein affects the reaction [afimoxifene results in increased expression of RGS16 mRNA]PMID:19153601
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