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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1588249
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zfp703
Name: zinc finger protein 703
Acc ID: CHEBI:44616
Term: afimoxifene
Definition: A tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen.
Chemical ID: MESH:C016601
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:16022086480464CTDafimoxifene inhibits the reaction [Estrogens results in increased expression of ZNF703 mRNA]

PMID:21233418
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