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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:44485
Term: N-ethylmaleimide
Definition: A member of the class of maleimides that is the N-ethyl derivative of maleimide.
Chemical ID: MESH:D005033
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1multiple interactionsISORGD:7325026480464CTDEthylmaleimide inhibits the reaction [APEX1 protein inhibits the reaction [Hydrogen Peroxide results in decreased activity of MAPK1 protein]]

PMID:23370007
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.