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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1a
Name: interleukin 1 alpha
Acc ID: CHEBI:44485
Term: N-ethylmaleimide
Definition: A member of the class of maleimides that is the N-ethyl derivative of maleimide.
Chemical ID: MESH:D005033
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1amultiple interactionsISORGD:7357076480464CTDEthylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA], Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]

PMID:7476933
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.