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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312751
Species: Homo sapiens
RGD Object: Gene
Symbol: FKBP3
Name: FKBP prolyl isomerase 3
Acc ID: CHEBI:44423
Term: hydroxyurea
Definition: A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.
Chemical ID: MESH:D006918
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13127526480464CTDHydroxyurea results in increased expression of FKBP3 mRNA

PMID:12929121
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.