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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2836
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b1
Name: hydroxysteroid (17-beta) dehydrogenase 1
Acc ID: CHEBI:44409
Term: NADP zwitterion
Definition: A NADP that has formula 743.40528.
Chemical ID: MESH:D009249
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b1multiple interactionsISOHSD17B1 (Homo sapiens)6480464CTD[HSD17B1 protein co-treated with NADP] results in increased reduction of Estrone; coumarin analog inhibits the reaction [[HSD17B1 protein co-treated with NADP] results in increased reduction of Estrone]; NADP binds to and results in increased activity of HSD17B1 proteinPMID:21232530 PMID:25526675
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