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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69480
Species: Homo sapiens
RGD Object: Gene
Symbol: PDK1
Name: pyruvate dehydrogenase kinase 1
Acc ID: CHEBI:44369
Term: duvoglustat
Definition: An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration.
Chemical ID: MESH:D017485
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDK1multiple interactionsISOPdk1 (Mus musculus)6480464CTD[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA]PMID:25446853
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