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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734356
Species: Homo sapiens
RGD Object: Gene
Symbol: JUN
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:44368
Term: nitrofurazone
Definition: A semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcers, wounds and skin infections.
Chemical ID: MESH:D009583
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUNincreases expressionISOJun (Rattus norvegicus)6480464CTDNitrofurazone results in increased expression of JUN mRNAPMID:15945272
JUNmultiple interactionsISOJun (Rattus norvegicus)6480464CTDAcetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of JUN mRNA]PMID:15945272
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