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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736015
Species: Homo sapiens
RGD Object: Gene
Symbol: ACACA
Name: acetyl-CoA carboxylase alpha
Acc ID: CHEBI:4429
Term: deoxypodophyllotoxin
Definition: A member of the class of furonaphthodioxoles that is (5R,5aR,8aR)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one substituted at position 5 by a 3,4,5-trimethoxyphenyl group.
Chemical ID: MESH:C014451
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACACAincreases phosphorylationEXP 6480464CTDdeoxypodophyllotoxin results in increased phosphorylation of ACACA proteinPMID:30148990
ACACAmultiple interactionsEXP 6480464CTDdeoxypodophyllotoxin inhibits the reaction [T0901317 results in increased expression of ACACA mRNA]PMID:30148990
ACACAmultiple interactionsISOAcaca (Mus musculus)6480464CTDdeoxypodophyllotoxin inhibits the reaction [Dietary Fats results in decreased phosphorylation of ACACA protein]PMID:30148990
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