GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL1A | decreases expression | EXP | | 6480464 | CTD | Methotrexate results in decreased expression of IL1A mRNA | PMID:17400583 | IL1A | increases expression | EXP | | 6480464 | CTD | Methotrexate results in increased expression of IL1A mRNA | PMID:17379860 PMID:19100307 PMID:24657277 | IL1A | multiple interactions | EXP | | 6480464 | CTD | [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of IL1A mRNA | PMID:24657277 | IL1A | multiple interactions | ISO | Il1a (Mus musculus) | 6480464 | CTD | [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein | PMID:31651976 | |
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