GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ABCC5 | decreases expression | EXP | | 6480464 | CTD | Methotrexate results in decreased expression of ABCC5 mRNA | PMID:23897011 | ABCC5 | decreases response to substance | EXP | | 6480464 | CTD | ABCC5 protein results in decreased susceptibility to Methotrexate | PMID:15897250 | ABCC5 | decreases response to substance | ISO | Abcc5 (Mus musculus) | 6480464 | CTD | ABCC5 mRNA results in decreased susceptibility to Methotrexate; ABCC5 protein results in decreased susceptibility to Methotrexate | PMID:16918715 | |
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