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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732554
Species: Homo sapiens
RGD Object: Gene
Symbol: GNE
Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Acc ID: CHEBI:44185
Term: methotrexate
Definition: A pteridine that has formula C20H22N8O5.
Chemical ID: MESH:D008727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GNEaffects response to substanceEXP 6480464CTDGNE protein affects the susceptibility to MethotrexatePMID:16217747
GNEaffects expressionISOGne (Mus musculus)6480464CTDMethotrexate affects the expression of GNE mRNAPMID:18502557
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