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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a23-3a1
Name: cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
Acc ID: CHEBI:44185
Term: methotrexate
Definition: A pteridine that has formula C20H22N8O5.
Chemical ID: MESH:D008727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a23-3a1decreases expressionEXP 6480464CTDMethotrexate results in decreased expression of CYP3A23-3A1 mRNAPMID:15120968 PMID:29027214
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