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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61967
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcm6
Name: minichromosome maintenance complex component 6
Acc ID: CHEBI:44185
Term: methotrexate
Definition: A pteridine that has formula C20H22N8O5.
Chemical ID: MESH:D008727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcm6decreases expressionISOMCM6 (Homo sapiens)6480464CTDMethotrexate results in decreased expression of MCM6 mRNAPMID:24657277
Mcm6multiple interactionsISOMCM6 (Homo sapiens)6480464CTD[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of MCM6 mRNAPMID:24657277
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