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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346747
Species: Homo sapiens
RGD Object: Gene
Symbol: H2BC14
Name: H2B clustered histone 14
Acc ID: CHEBI:44185
Term: methotrexate
Definition: A pteridine that has formula C20H22N8O5.
Chemical ID: MESH:D008727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDMethotrexate results in decreased expression of H2BC14 mRNA

PMID:24449571, PMID:24657277
multiple interactionsEXP 6480464CTD[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of H2BC14 mRNA

PMID:24657277
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.