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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621120
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk4
Name: cyclin-dependent kinase 4
Acc ID: CHEBI:44107
Term: malachite green cation
Definition: An iminium ion obtained by dimethylation of the imino group of 4-{[4-(dimethylamino)phenyl](phenyl)methylene}cyclohexa-2,5-dien-1-imine. Used in the form of its chloride salt as a green-coloured dye.
Chemical ID: MESH:C005095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk4multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK4 mRNA, [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK4 protein

PMID:12616621
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