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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735795
Species: Mus musculus
RGD Object: Gene
Symbol: Chrnb2
Name: cholinergic receptor nicotinic beta 2 subunit
Acc ID: CHEBI:43931
Term: methyllycaconitine
Definition: A diterpenoid that has formula C37H50N2O10.
Chemical ID: MESH:C054634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrnb2multiple interactionsISOChrnb2 (Rattus norvegicus)2303194RGDmethyllycaconitine affects binding to Chrnb2 protein; methyllycaconitine competes with [Epibatidine binds to Chrnb2 protein] 
Chrnb2multiple interactionsISOCHRNB2 (Homo sapiens)6480464CTDCarbachol inhibits the reaction [methyllycaconitine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; methyllycaconitine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; methyllycaconitine inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; methyllycaconitine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]PMID:14645658
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