GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk3 | increases phosphorylation | ISO | MAPK3 (Homo sapiens) | 6480464 | CTD | methyllycaconitine results in increased phosphorylation of MAPK3 protein | PMID:24012499 | Mapk3 | multiple interactions | ISO | MAPK3 (Homo sapiens) | 6480464 | CTD | [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein]; MAPK3 mutant form inhibits the reaction [methyllycaconitine results in increased expression of SRR protein]; methyllycaconitine inhibits the reaction [Varenicline results in increased phosphorylation of MAPK3 protein] | PMID:18448488 PMID:24012499 PMID:28842382 | Mapk3 | multiple interactions | ISO | Mapk3 (Mus musculus) | 6480464 | CTD | methyllycaconitine inhibits the reaction [Varenicline results in increased phosphorylation of MAPK3 protein] | PMID:28202387 | | ||||||||||||||||||||||
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