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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1561123
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itgax
Name: integrin subunit alpha X
Acc ID: CHEBI:43645
Term: indirubin-3'-monoxime
Definition: A member of the class of biindoles that is indirubin in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.
Chemical ID: MESH:C474021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgaxdecreases expressionISOItgax (Mus musculus)6480464CTDindirubin-3'-monoxime results in decreased expression of ITGAX proteinPMID:21948866
Itgaxmultiple interactionsISOItgax (Mus musculus)6480464CTDAHR protein affects the susceptibility to [indirubin-3'-monoxime results in decreased expression of ITGAX protein]; indirubin-3'-monoxime inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAX protein]PMID:21948866
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