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RGD ID: 1316378
Species: Mus musculus
RGD Object: Gene
Symbol: Rps6ka4
Name: ribosomal protein S6 kinase, polypeptide 4
Acc ID: CHEBI:43602
Term: obeticholic acid
Definition: A dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis.
Chemical ID: MESH:C464660
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rps6ka4decreases expressionISORGD:13163776480464CTDobeticholic acid results in decreased expression of RPS6KA4 mRNA

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.