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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:4357
Term: Deguelin
Definition: An isoflavanone that has formula C23H22O6.
Chemical ID: MESH:C107676
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDdeguelin inhibits the reaction [Oxygen deficiency results in decreased expression of IL4 mRNA]

PMID:22745725
multiple interactionsISORGD:107966480464CTDdeguelin inhibits the reaction [OVAL protein results in increased expression of IL4 mRNA], deguelin inhibits the reaction [OVAL protein results in increased expression of IL4 protein]

PMID:28529457
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.