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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10588
Species: Mus musculus
RGD Object: Gene
Symbol: Fhl1
Name: four and a half LIM domains 1
Acc ID: CHEBI:42977
Term: 25-hydroxycholesterol
Definition: A 25-hydroxy steroid that has formula 402.65294.
Chemical ID: MESH:C007997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fhl1increases expressionISOFhl1 (Rattus norvegicus)6480464CTD25-hydroxycholesterol results in increased expression of FHL1 mRNAPMID:17161435
Fhl1multiple interactionsISOFhl1 (Rattus norvegicus)6480464CTD15-deoxyprostaglandin J2 inhibits the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA]; alitretinoin promotes the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA]; Brefeldin A inhibits the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA]; Cycloheximide promotes the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA]; Dactinomycin promotes the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA]; Genistein inhibits the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA]PMID:17161435
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