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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732449
Species: Mus musculus
RGD Object: Gene
Symbol: Nphs2
Name: nephrosis 2, podocin
Acc ID: CHEBI:42839
Term: 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Definition: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.
Chemical ID: MESH:D011692
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nphs2decreases expressionEXP 6480464CTDPuromycin Aminonucleoside results in decreased expression of NPHS2 proteinPMID:18509322
Nphs2multiple interactionsEXP 6480464CTDtriptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS2 protein]PMID:18509322
Nphs2affects expressionISONphs2 (Rattus norvegicus)6480464CTDPuromycin Aminonucleoside affects the expression of NPHS2 mRNA; Puromycin Aminonucleoside affects the expression of NPHS2 proteinPMID:15363039
Nphs2decreases expressionISONphs2 (Rattus norvegicus)6480464CTDPuromycin Aminonucleoside results in decreased expression of NPHS2 proteinPMID:12065681 PMID:18509322
Nphs2multiple interactionsISONphs2 (Rattus norvegicus)6480464CTDtriptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS2 protein]PMID:18509322
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