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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619864
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabbr2
Name: gamma-aminobutyric acid type B receptor subunit 2
Acc ID: CHEBI:42797
Term: gabapentin
Definition: A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Chemical ID: MESH:C040029
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabbr2multiple interactionsISORGD:7317546480464CTDCGP 71872 inhibits the reaction [Gabapentin binds to and results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein]] Gabapentin binds to and results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein]

PMID:11125035
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