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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2948
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aadat
Name: aminoadipate aminotransferase
Acc ID: CHEBI:42797
Term: gabapentin
Definition: A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Chemical ID: MESH:C040029
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases activityEXP 6480464CTDgabapentin results in decreased activity of AADAT protein

PMID:16765940
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.