GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccn2 | increases expression | EXP | | 6480464 | CTD | Glucose results in increased expression of CCN2 mRNA; Glucose results in increased expression of CCN2 protein | PMID:14586741 PMID:22031849 PMID:26891083 | Ccn2 | multiple interactions | EXP | | 6480464 | CTD | Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]; CCN2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]; fatostatin inhibits the reaction [Glucose results in increased expression of CCN2 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of CCN2 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of CCN2 protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of CCN2 protein]] | PMID:14586741 PMID:21124846 PMID:22031849 PMID:26891083 | Ccn2 | increases expression | ISO | CCN2 (Homo sapiens) | 6480464 | CTD | Glucose results in increased expression of CCN2 mRNA; Glucose results in increased expression of CCN2 protein | PMID:10026205 PMID:19369054 PMID:21367880 | Ccn2 | increases expression | ISO | Ccn2 (Mus musculus) | 6480464 | CTD | Glucose results in increased expression of CCN2 mRNA | PMID:33270355 | Ccn2 | multiple interactions | ISO | CCN2 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]; Cadmium inhibits the reaction [Glucose results in increased expression of CCN2 protein]; CCL2 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Glucose results in increased expression of CCN2 protein] | PMID:10026205 PMID:19369054 PMID:21367880 | Ccn2 | multiple interactions | ISO | Ccn2 (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] | PMID:33270355 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |