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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aco2
Name: aconitase 2
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aco2multiple interactionsEXP 6480464CTD[Glucose co-treated with Oxygen] affects the activity of ACO2 protein; Glucose results in decreased expression of and results in decreased activity of ACO2 protein; LONP1 protein affects the reaction [SRT1720 inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of ACO2 protein]]; manganese tetrakis-(N-ethyl-2 pyridyl) porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]; SRT1720 inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of ACO2 protein]PMID:11520895 PMID:31639451
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