GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkbia | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of NFKBIA protein | PMID:23376009 PMID:31323227 | Nfkbia | increases expression | EXP | | 6480464 | CTD | Glucose results in increased expression of NFKBIA protein; Glucose results in increased expression of NFKBIA protein modified form | PMID:23770986 | Nfkbia | increases phosphorylation | EXP | | 6480464 | CTD | Glucose results in increased phosphorylation of NFKBIA protein | PMID:24971582 | Nfkbia | multiple interactions | EXP | | 6480464 | CTD | 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Glucose results in decreased expression of NFKBIA protein]; [Glucose co-treated with IGF2R protein modified form] results in decreased expression of NFKBIA protein; [Glucose co-treated with IGF2R protein modified form] results in decreased expression of NFKBIA protein modified form; Glucose results in increased phosphorylation of and results in increased degradation of NFKBIA protein; prolinedithiocarbamate inhibits the reaction [Glucose results in decreased expression of NFKBIA protein]; pyrazolanthrone inhibits the reaction [Glucose results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Quercetin inhibits the reaction [Glucose results in increased expression of NFKBIA protein modified form]; Quercetin inhibits the reaction [Glucose results in increased expression of NFKBIA protein]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Glucose results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Y 27632 inhibits the reaction [Glucose results in decreased expression of NFKBIA protein] | PMID:22245600 PMID:23376009 PMID:23770986 PMID:24971582 PMID:31323227 PMID:36462176 | Nfkbia | increases expression | ISO | Nfkbia (Mus musculus) | 6480464 | CTD | Glucose results in increased expression of NFKBIA mRNA | PMID:17178593 | Nfkbia | increases phosphorylation | ISO | Nfkbia (Mus musculus) | 6480464 | CTD | Glucose results in increased phosphorylation of NFKBIA protein | PMID:17065336 PMID:30101366 | Nfkbia | increases phosphorylation | ISO | NFKBIA (Homo sapiens) | 6480464 | CTD | Glucose results in increased phosphorylation of NFKBIA protein | PMID:19132243 | Nfkbia | multiple interactions | ISO | Nfkbia (Mus musculus) | 6480464 | CTD | [Oxygen deficiency co-treated with Glucose deficiency] results in increased degradation of NFKBIA protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of and results in increased degradation of NFKBIA protein; [Ribose co-treated with Glucose] results in increased phosphorylation of NFKBIA protein; acetovanillone inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; INO 1001 inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; Prodigiosin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased degradation of NFKBIA protein]; prolinedithiocarbamate inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased degradation of NFKBIA protein] | PMID:16395278 PMID:17065336 PMID:21925195 PMID:30101366 | Nfkbia | multiple interactions | ISO | NFKBIA (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; Catechin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; Glucose results in increased degradation of and results in decreased expression of NFKBIA protein; Luteolin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; Quercetin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; Rutin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; SB 203580 inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein] | PMID:19132243 PMID:19557821 | | ||||||||||||||||||||||
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